{"product_id":"tensin-1-phospho-tyr1326-rabbit-pab-es1531","title":"Tensin-1 (phospho Tyr1326) rabbit pAb - ES1531","description":"\u003cp\u003eTensin-1 (phospho Tyr1326) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES1531-50, ES1531-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: TNS1; TNS; Tensin-1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized phospho-peptide around the phosphorylation site of human Tensin-1 (phospho Tyr1326)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 185kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 7145\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9HBL0\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell surface. Cell junction, focal adhesion. Cytoplasm, cytoskeleton. Localized at cell periphery preferentially to fibrillar adhesions than focal adhesions. Translocates from the cell edge to cell center in an ITGB1BP1-dependent manner.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202020827315,"sku":"ES1531-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202020860083,"sku":"ES1531-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_3538598d-3803-4d51-afdc-0c57a6eca35e.png?v=1767120052","url":"https:\/\/afsbio.com\/products\/tensin-1-phospho-tyr1326-rabbit-pab-es1531","provider":"AFSBio Inc.","version":"1.0","type":"link"}