{"product_id":"tgfβ2-polyclonal-antibody-ra20515","title":"TGFβ2 Polyclonal Antibody - RA20515","description":"TGFβ2 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA20515-50, RA20515-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: transforming growth factor beta 2 (TGFB2) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta\/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the an\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/20000. Not yet tested in other applications.\n\nAlternative Names: TGFB2; Transforming growth factor beta-2; TGF-beta-2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; Polyergin\n\nApplications: WB; IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 7042\n\nProtein MW (KDa): 44\n\nSWISS: P61812\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120675905715,"sku":"RA20515-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120675938483,"sku":"RA20515-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_02b990d3-d070-43d2-bff9-e98a3992cfab.png?v=1773369289","url":"https:\/\/afsbio.com\/products\/tgf%ce%b22-polyclonal-antibody-ra20515","provider":"AFSBio Inc.","version":"1.0","type":"link"}