{"product_id":"tgf-beta-1-polyclonal-antibody-bt-ap08145","title":"TGF beta 1 Polyclonal Antibody - BT-AP08145","description":"\u003cp\u003eTGF beta 1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08145-20, BT-AP08145-50, BT-AP08145-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide| and is found in either a latent form composed of a mature peptide homodimer| a LAP homodimer| and a latent TGF-beta binding protein| or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation| differentiation and growth| and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene i\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Stem cells; Cancer; Metabolism; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TGFB1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Transforming growth factor beta-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P01137; Mouse: P04202; Rat: P17246\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Transforming growth factor beta-1 (TGF-beta-1) [Cleaved into: Latency-associated peptide (LAP)]; Transforming growth factor beta-1; TGF-beta-1; Latency-associated peptide; LAP;\u003c\/p\u003e \n\n\u003cp\u003eGeneID: Human: 7040; Mouse: 21803; Rat: 59086\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238978609331,"sku":"BT-AP08145-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238978642099,"sku":"BT-AP08145-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238978674867,"sku":"BT-AP08145-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b7eabcdc-95a0-4cf0-8c84-d11579163cbb.png?v=1769387486","url":"https:\/\/afsbio.com\/products\/tgf-beta-1-polyclonal-antibody-bt-ap08145","provider":"AFSBio Inc.","version":"1.0","type":"link"}