{"product_id":"tgf-beta-ri-polyclonal-antibody-bt-ap08970","title":"TGF Beta RI Polyclonal Antibody - BT-AP08970","description":"\u003cp\u003eTGF Beta RI Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08970-20, BT-AP08970-50, BT-AP08970-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: TGF-beta receptor type-1 encoded by TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The TGF-beta receptor type-1 is a serine\/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TGFBR1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TGFbeta RI Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 55960\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P36897; Mouse: Q64729; Rat: P80204\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TGFBR1; ALK5; SKR4; TGF-beta receptor type-1; TGFR-1; Activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ALK-5; ALK5; Serine\/threonine-protein kinase receptor R4;\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7046; Mouse: 21812\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239946281139,"sku":"BT-AP08970-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239946313907,"sku":"BT-AP08970-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239946346675,"sku":"BT-AP08970-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ee8a7251-8329-4dcb-8baa-171c787b001b.png?v=1769401284","url":"https:\/\/afsbio.com\/products\/tgf-beta-ri-polyclonal-antibody-bt-ap08970","provider":"AFSBio Inc.","version":"1.0","type":"link"}