{"product_id":"tgfb1-monoclonal-antibody-bt-mca3693","title":"TGFb1 Monoclonal Antibody - BT-MCA3693","description":"\u003cp\u003eTGFb1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3693-50, BT-MCA3693-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction, Cancer, Metabolism, Stem cells, Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TGFb1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 7F6\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TGFb1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human TGFb1 (AA: 62-195) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 44.3kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P01137\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CED, LAP, DPD1, TGFB, TGFbeta\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7040\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238578806963,"sku":"BT-MCA3693-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238578839731,"sku":"BT-MCA3693-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3794045b-70cd-446e-93e9-2a4146f93beb.png?v=1769382760","url":"https:\/\/afsbio.com\/products\/tgfb1-monoclonal-antibody-bt-mca3693","provider":"AFSBio Inc.","version":"1.0","type":"link"}