{"product_id":"thrombomodulin-polyclonal-antibody-bs91345","title":"Thrombomodulin Polyclonal Antibody-BS91345","description":"\u003cp\u003eThrombomodulin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS91345-50, BS91345-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P07204(Human)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB:1:500-1:2,000\u003cbr\u003e\nIHC:1:50-1:200\u003cbr\u003e\nIP:1:10-1:50\u003c\/p\u003e\n\n\u003cp\u003eBackground: Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Thrombomodulin polyclonal antibody detects endogenous levels of Thrombomodulin protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 100 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of Thrombomodulin on A431 cell using anti-Thrombomodulin antibody at 1\/500 dilution., Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-Thrombomodulin antibody. Counter stained with hematoxylin.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: TM, THBD, THRM, AHUS 6, AHUS6, BDCA 3, BDCA3, CD 141, CD141, CD141 antigen, Fetomodulin, Thbd, THPH12, THRM, Thrombomodulin, TM, TRBM,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42987055743155,"sku":"BS91345-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42987055775923,"sku":"BS91345-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_ca0e6cf4-a4d4-44cd-831d-d22332bea551.jpg?v=1706007982","url":"https:\/\/afsbio.com\/products\/thrombomodulin-polyclonal-antibody-bs91345","provider":"AFSBio Inc.","version":"1.0","type":"link"}