{"product_id":"tie1-phospho-tyr1117-rabbit-polyclonal-antibody-ra36842","title":"TIE1 (Phospho-Tyr1117) Rabbit Polyclonal Antibody - RA36842","description":"\u003cp\u003eTIE1 (Phospho-Tyr1117) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA36842-50, RA36842-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: tyrosine kinase with immunoglobulin like and EGF like domains 1 (TIE1) Homo sapiens This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.158% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 7075\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P35590\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120380141747,"sku":"RA36842-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120380174515,"sku":"RA36842-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b5a05a20-7f7e-40f9-ba3b-040c242c7d96.png?v=1773364265","url":"https:\/\/afsbio.com\/products\/tie1-phospho-tyr1117-rabbit-polyclonal-antibody-ra36842","provider":"AFSBio Inc.","version":"1.0","type":"link"}