{"product_id":"tie2-phospho-ser1119-rabbit-polyclonal-antibody-bt-ap05107","title":"Tie2 (Phospho-Ser1119) Rabbit Polyclonal Antibody - BT-AP05107","description":"\u003cp\u003eTie2 (Phospho-Ser1119) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05107-20, BT-AP05107-50, BT-AP05107-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains| three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described| but their full-length nature is not known.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Stem cells; Developmental biology; Cancer; Cardiovascular; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TEK\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Tie2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q02763; Mouse: Q02858\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Tie2;Ser1119; Angiopoietin-1 receptor; EC 2.7.10.1; Endothelial tyrosine kinase; Tunica interna endothelial cell kinase; Tyrosine kinase with Ig and EGF homology domains-2; Tyrosine-protein kinase receptor TEK; Tyrosine-protein kinase receptor TIE-2; hTIE2; p140 TEK; CD antigen CD202b\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7010\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239027073203,"sku":"BT-AP05107-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239027105971,"sku":"BT-AP05107-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239027138739,"sku":"BT-AP05107-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c6c5b8a6-45f3-448b-94b6-f78be2c6c7f2.png?v=1769388097","url":"https:\/\/afsbio.com\/products\/tie2-phospho-ser1119-rabbit-polyclonal-antibody-bt-ap05107","provider":"AFSBio Inc.","version":"1.0","type":"link"}