{"product_id":"tig1-polyclonal-antibody-bt-ap14965","title":"TIG1 Polyclonal Antibody - BT-AP14965","description":"\u003cp\u003eTIG1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14965-20, BT-AP14965-50, BT-AP14965-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RARRES1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Retinoic acid receptor responder protein 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P49788\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Retinoic acid receptor responder protein 1;RAR-responsive protein TIG1;Tazarotene-induced gene 1 protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5918\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239388537011,"sku":"BT-AP14965-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239388569779,"sku":"BT-AP14965-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239388602547,"sku":"BT-AP14965-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_efa3ca67-58c1-4ab4-8172-1dcc6b8c1749.png?v=1769393838","url":"https:\/\/afsbio.com\/products\/tig1-polyclonal-antibody-bt-ap14965","provider":"AFSBio Inc.","version":"1.0","type":"link"}