{"product_id":"tig3-polyclonal-antibody-bt-ap14967","title":"TIG3 Polyclonal Antibody - BT-AP14967","description":"\u003cp\u003eTIG3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14967-20, BT-AP14967-50, BT-AP14967-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RARRES3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Retinoic acid receptor responder protein 3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UL19\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Retinoic acid receptor responder protein 3;EC 3.1.1.-;RAR-responsive protein TIG3;Retinoid-inducible gene 1 protein;Tazarotene-induced gene 3 protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5920\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239388733619,"sku":"BT-AP14967-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239388766387,"sku":"BT-AP14967-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239388799155,"sku":"BT-AP14967-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4a307daa-5eba-4c2b-9e6d-1bfa40a62607.png?v=1769393841","url":"https:\/\/afsbio.com\/products\/tig3-polyclonal-antibody-bt-ap14967","provider":"AFSBio Inc.","version":"1.0","type":"link"}