{"product_id":"tim-3-havcr2-polyclonal-antibody-e-ab-64640","title":"TIM-3\/HAVCR2 Polyclonal Antibody - E-AB-64640","description":"\u003cp\u003eTIM-3\/HAVCR2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-64640-60, E-AB-64640-120, E-AB-64640-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TIM-3\/HAVCR2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: HAVCR2; CD366; HAVcr-2; KIM-3; TIM3; TIMD-3; TIMD3; Tim-3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q8TDQ0\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human TIM-3\/HAVCR2 (NP_116171.3).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF 1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136900497587,"sku":"E-AB-64640-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136900530355,"sku":"E-AB-64640-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136900563123,"sku":"E-AB-64640-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_14919f77-5825-4f65-8bd2-b718649c11f8.png?v=1709993689","url":"https:\/\/afsbio.com\/products\/tim-3-havcr2-polyclonal-antibody-e-ab-64640","provider":"AFSBio Inc.","version":"1.0","type":"link"}