{"product_id":"tim3-monoclonal-antibody-bt-mca4723","title":"TIM3 Monoclonal Antibody - BT-MCA4723","description":"\u003cp\u003eTIM3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4723-50, BT-MCA4723-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TIM3\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5A7D12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TIM3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human TIM3 (AA: 224-301) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 33.4kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q8TDQ0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HAVCR2, CD366, KIM-3, TIMD3, Tim-3, TIMD-3, HAVcr-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 84868\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238421225651,"sku":"BT-MCA4723-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238421258419,"sku":"BT-MCA4723-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_173a2dbc-b8b7-4ba5-b6ac-6a2650aa665d.png?v=1769380488","url":"https:\/\/afsbio.com\/products\/tim3-monoclonal-antibody-bt-mca4723","provider":"AFSBio Inc.","version":"1.0","type":"link"}