{"product_id":"tim50-rabbit-polyclonal-antibody-bt-ap05119","title":"TIM50 Rabbit Polyclonal Antibody - BT-AP05119","description":"\u003cp\u003eTIM50 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05119-20, BT-AP05119-50, BT-AP05119-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal| or presequence| on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier| and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TIMM50\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TIM50\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q3ZCQ8; Mouse: Q9D880\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TIM50; Mitochondrial import inner membrane translocase subunit TIM50\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 92609; Mouse: 66525\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239027368115,"sku":"BT-AP05119-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239027400883,"sku":"BT-AP05119-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239027433651,"sku":"BT-AP05119-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8bfff9af-9b80-42ca-9f3b-7d5a1c799d95.png?v=1769388101","url":"https:\/\/afsbio.com\/products\/tim50-rabbit-polyclonal-antibody-bt-ap05119","provider":"AFSBio Inc.","version":"1.0","type":"link"}