{"product_id":"timeless-polyclonal-antibody-e-ab-67609","title":"TIMELESS Polyclonal Antibody - E-AB-67609","description":"\u003cp\u003eTIMELESS Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67609-60, E-AB-67609-120, E-AB-67609-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TIMELESS\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TIMELESS; TIM; TIM1; hTIM\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9UNS1\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK\/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TIMELESS (NP_003911.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 138kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 160kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148686295219,"sku":"E-AB-67609-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148686327987,"sku":"E-AB-67609-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148686360755,"sku":"E-AB-67609-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d089f3ad-37a4-4ec7-8de3-faeaab06e7ea.png?v=1710328039","url":"https:\/\/afsbio.com\/products\/timeless-polyclonal-antibody-e-ab-67609","provider":"AFSBio Inc.","version":"1.0","type":"link"}