{"product_id":"tin2-rabbit-pab-es5486","title":"TIN2 rabbit pAb - ES5486","description":"\u003cp\u003eTIN2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5486-50, ES5486-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: TINF2; TIN2; TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human TINF2. AA range:71-120\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 53kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 26277\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9BSI4\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Chromosome, telomere. Associated with telomeres.; [Isoform 1]: Nucleus matrix.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202250072243,"sku":"ES5486-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202250105011,"sku":"ES5486-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_10f3d281-b933-4f4a-92d4-92ff977fba46.png?v=1767125118","url":"https:\/\/afsbio.com\/products\/tin2-rabbit-pab-es5486","provider":"AFSBio Inc.","version":"1.0","type":"link"}