{"product_id":"titin-cmd1g-polyclonal-antibody-bs65480","title":"Titin\/CMD1G Polyclonal Antibody - BS65480","description":"\u003cp\u003eTitin\/CMD1G Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS65480-50, BS65480-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Titin, also known as connectin, is a large protein involved in the temporal and spatial control of the assembly of the highly ordered sarcomeres (contractile units) of striated muscle. In addition to sarcomere assembly Titin also functions to maintain the structural integrity of the contracting myofibrils within the muscle and to organize the machinery for condensation of chromosomes in dividing cells. Titin is a giant protein composed of 27, 000 amino acids and contains an autoregμlated serine kinase catalytic domain as well as a calcium\/calmodμlin binding region that are involved in its activation. Activated Titin phosphorylates the muscle protein telethonin, a sarcomeric protein abundant in heart and skeletal muscle, implicating Titin activity in the reorganization of the cytoskeleton during myofibrillogenesis.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Pig, Cow\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: ELISA, IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: TTN, MPRM, Cardiomyopathy dilated 1G (autosomal dominant), CMD1G, CMH 9, CMH9, CMPD 4, CMPD4, Connectin, DKFZp451N061, EOMFC, HMERF, LGMD2J, MU RMS 40.14, Rhabdomyosarcoma antigen, Rhabdomyosarcoma antigen MU RMS 40.14, Rhabdomyosarcoma antigen MU-RMS-40.14, TITIN_HUMAN, TMD.\u003c\/p\u003e \n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: KLH conjugated synthetic peptide derived from human Titin\/CMD1G:2601-2800\/34350\u003c\/p\u003e \n\n\u003cp\u003eDilution: ELISA=1:5000-10000\u003cbr\u003e\nIHC=1:100-500\u003c\/p\u003e\n\n\u003cp\u003ePurification: affinity purified by Protein A\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Titin\/CMD1G Polyclonal Antibody detects endogenous levels of Titin\/CMD1G protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 3780 kD\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q8WZ42\u003c\/p\u003e\n\n\u003cp\u003eProduct: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45938535989427,"sku":"BS65480-50","price":349.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45938536022195,"sku":"BS65480-100","price":582.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_7d54f7f7-895a-4faa-805b-93c7ca9b170c.jpg?v=1788296274","url":"https:\/\/afsbio.com\/products\/titin-cmd1g-polyclonal-antibody-bs65480","provider":"AFSBio Inc.","version":"1.0","type":"link"}