{"product_id":"tle2-polyclonal-antibody-bt-ap09052","title":"TLE2 Polyclonal Antibody - BT-AP09052","description":"\u003cp\u003eTLE2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09052-20, BT-AP09052-50, BT-AP09052-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD-repeats implicated in protein-protein interaction. TLEs are transcriptional co-repressors that bind to many transcription factors such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TLE2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TLE2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 79841\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q04725; Mouse: Q9WVB2\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TLE2; Transducin-like enhancer protein 2; Enhancer of split groucho-like protein 2; ESG2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7089\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239951818931,"sku":"BT-AP09052-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239951851699,"sku":"BT-AP09052-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239951884467,"sku":"BT-AP09052-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9e8c1ec9-e856-4d0d-b338-c9a047b69f1e.png?v=1769401346","url":"https:\/\/afsbio.com\/products\/tle2-polyclonal-antibody-bt-ap09052","provider":"AFSBio Inc.","version":"1.0","type":"link"}