{"product_id":"tle3-rabbit-polyclonal-antibody-bt-ap05128","title":"TLE3 Rabbit Polyclonal Antibody - BT-AP05128","description":"\u003cp\u003eTLE3 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP05128-20, BT-AP05128-50, BT-AP05128-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described| but their full-length nature is not known.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TLE3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TLE3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q04726; Mouse: Q08122; Rat: Q9JIT3\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TLE3; Transducin-like enhancer protein 3; Enhancer of split groucho-like protein 3; ESG3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7090; Mouse: 21887; Rat: 84424\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239027499187,"sku":"BT-AP05128-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239027531955,"sku":"BT-AP05128-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239027564723,"sku":"BT-AP05128-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3ccf7e89-9910-4f93-9cb0-9b2cd5c56bbd.png?v=1769388103","url":"https:\/\/afsbio.com\/products\/tle3-rabbit-polyclonal-antibody-bt-ap05128","provider":"AFSBio Inc.","version":"1.0","type":"link"}