{"product_id":"tlk1-rabbit-pab-es3616","title":"TLK1 rabbit pAb - ES3616","description":"\u003cp\u003eTLK1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3616-50, ES3616-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Serine\/threonine-protein kinase tousled-like 1 encoded by TLK1 is a serine\/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: TLK1; KIAA0137; Serine\/threonine-protein kinase tousled-like 1; PKU-beta; Tousled-like kinase 1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human TLK1. AA range:201-250\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 87kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 9874\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9UKI8\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202144755891,"sku":"ES3616-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202144788659,"sku":"ES3616-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_f19e21d0-98b2-4b6c-a64e-a3c3b0839b80.png?v=1767122951","url":"https:\/\/afsbio.com\/products\/tlk1-rabbit-pab-es3616","provider":"AFSBio Inc.","version":"1.0","type":"link"}