{"product_id":"tlr1-polyclonal-antibody-e-ab-65724","title":"TLR1 Polyclonal Antibody - E-AB-65724","description":"\u003cp\u003eTLR1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-65724-60, E-AB-65724-120, E-AB-65724-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TLR1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TLR1; CD281; TIL; TIL. LPRS5; rsc786; TIL.LPRS5\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology, Signaling transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q15399\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and\/or from alternative splicing, have been noted for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TLR1 (NP_003254.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 90kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 100kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146384015539,"sku":"E-AB-65724-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146384048307,"sku":"E-AB-65724-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146384081075,"sku":"E-AB-65724-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_97b68f3c-632d-4ca8-9b0a-9ed0897dc108.png?v=1710294648","url":"https:\/\/afsbio.com\/products\/tlr1-polyclonal-antibody-e-ab-65724","provider":"AFSBio Inc.","version":"1.0","type":"link"}