{"product_id":"tlr2-monoclonal-antibody-bt-mca3437","title":"TLR2 Monoclonal Antibody - BT-MCA3437","description":"\u003cp\u003eTLR2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3437-50, BT-MCA3437-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction, Immunology, Microbiology, Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TLR2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2D6\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TLR2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human TLR2 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 100kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O60603\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TIL4, CD282, TLR2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7097\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238633136307,"sku":"BT-MCA3437-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238633169075,"sku":"BT-MCA3437-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c9eb1b19-134c-4764-aeb0-234a5ce35d49.png?v=1769383264","url":"https:\/\/afsbio.com\/products\/tlr2-monoclonal-antibody-bt-mca3437","provider":"AFSBio Inc.","version":"1.0","type":"link"}