{"product_id":"tlr5-polyclonal-antibody-e-ab-10872","title":"TLR5 Polyclonal Antibody - E-AB-10872","description":"\u003cp\u003eTLR5 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-10872-60, E-AB-10872-120, E-AB-10872-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TLR5\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: FLJ10052; MGC126430; MGC126431; SLEB1; TIL 3; TIL3; TLR 5; Tlr5; TLR5; Toll like receptor 5; Toll like receptor 5 precursor; Toll-like receptor 5; Toll\/interleukin 1 receptor like protein 3; Toll\/interleukin-1 receptor-like protein 3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Immunology\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O60602\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.3 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human TLR5\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124060979379,"sku":"E-AB-10872-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124061012147,"sku":"E-AB-10872-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124061044915,"sku":"E-AB-10872-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_84cbf1a5-43ed-4c33-bf4c-b69d2682a25f.png?v=1709723189","url":"https:\/\/afsbio.com\/products\/tlr5-polyclonal-antibody-e-ab-10872","provider":"AFSBio Inc.","version":"1.0","type":"link"}