{"product_id":"tm2d1-polyclonal-antibody-bt-ap15015","title":"TM2D1 Polyclonal Antibody - BT-AP15015","description":"\u003cp\u003eTM2D1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15015-20, BT-AP15015-50, BT-AP15015-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimerandapos;s disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Signal transduction; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TM2D1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TM2 domain-containing protein 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9BX74; Mouse: Q99MB3\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TM2 domain-containing protein 1;Beta-amyloid-binding protein;hBBP\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 83941\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239390863539,"sku":"BT-AP15015-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239390896307,"sku":"BT-AP15015-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239390929075,"sku":"BT-AP15015-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d11b2a0f-54be-476f-9931-6912438ef338.png?v=1769393878","url":"https:\/\/afsbio.com\/products\/tm2d1-polyclonal-antibody-bt-ap15015","provider":"AFSBio Inc.","version":"1.0","type":"link"}