{"product_id":"tm7sf2-polyclonal-antibody-e-ab-13736","title":"TM7SF2 Polyclonal Antibody - E-AB-13736","description":"\u003cp\u003eTM7SF2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-13736-60, E-AB-13736-120, E-AB-13736-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TM7SF2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ANG1; NET47; DHCR14A\u003c\/p\u003e\n\n \n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O76062\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4\/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4, 4-dimethyl-5-alpha-cholesta-8, 14, 24-trien-3-beta-ol to 4, 4-dimethyl-5-alpha-cholesta-8, 24-dien-3-beta-ol and NADP+.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human TM7SF2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 46kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146700062899,"sku":"E-AB-13736-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146700095667,"sku":"E-AB-13736-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146700128435,"sku":"E-AB-13736-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_fb687db5-2372-43c3-b74b-4ee4f2991f92.png?v=1710300398","url":"https:\/\/afsbio.com\/products\/tm7sf2-polyclonal-antibody-e-ab-13736","provider":"AFSBio Inc.","version":"1.0","type":"link"}