{"product_id":"tmc8-polyclonal-antibody-ra30553","title":"TMC8 Polyclonal Antibody - RA30553","description":"\u003cp\u003eTMC8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA30553-50, RA30553-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: transmembrane channel like 8 (TMC8) Homo sapiens Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: TMC8; EVER2; EVIN2; Transmembrane channel-like protein 8; Epidermodysplasia verruciformis protein 2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF (paraffin section) ; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 147138\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 81\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q8IU68\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122445115571,"sku":"RA30553-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122445148339,"sku":"RA30553-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8d14d156-b8dc-436f-91c5-cc6b33b8d628.png?v=1773348957","url":"https:\/\/afsbio.com\/products\/tmc8-polyclonal-antibody-ra30553","provider":"AFSBio Inc.","version":"1.0","type":"link"}