{"product_id":"tmed10-polyclonal-antibody-e-ab-61352","title":"TMED10 Polyclonal Antibody - E-AB-61352","description":"\u003cp\u003eTMED10 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61352-60, E-AB-61352-120, E-AB-61352-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TMED10\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TMED10; P24(DELTA); S31I125; S31III125; TMP21; Tmp-21-I; p23; p24d1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P49755\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the EMP24\/GP25L\/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TMED10 (NP_006818.3).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC \t1:50-1:200   IF \t1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136845152435,"sku":"E-AB-61352-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136845185203,"sku":"E-AB-61352-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136845217971,"sku":"E-AB-61352-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b5535c5d-4fef-499b-9d2e-3418f5578361.png?v=1709992603","url":"https:\/\/afsbio.com\/products\/tmed10-polyclonal-antibody-e-ab-61352","provider":"AFSBio Inc.","version":"1.0","type":"link"}