{"product_id":"tmprss11f-polyclonal-antibody-e-ab-13740","title":"TMPRSS11F Polyclonal Antibody - E-AB-13740","description":"\u003cp\u003eTMPRSS11F Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-13740-60, E-AB-13740-120, E-AB-13740-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TMPRSS11F\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Transmembrane protease serine 11F; TMPRSS11F; Airway trypsin-like protease 4\u003c\/p\u003e\n\n \n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q6ZWK6\u003c\/p\u003e\n\n\u003cp\u003eBackground: TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.7 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human TMPRSS11F\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:25-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 49kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146700161203,"sku":"E-AB-13740-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146700193971,"sku":"E-AB-13740-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146700226739,"sku":"E-AB-13740-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5ec2fe8b-0b6a-4f16-8a2c-1d933271b38b.png?v=1710300400","url":"https:\/\/afsbio.com\/products\/tmprss11f-polyclonal-antibody-e-ab-13740","provider":"AFSBio Inc.","version":"1.0","type":"link"}