{"product_id":"tnf-receptor-2-polyclonal-antibody-bz16979","title":"TNF Receptor 2 Polyclonal Antibody-BZ16979","description":"\u003cp\u003eTNF Receptor 2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16979-50, BZ16979-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P20333\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-F, IHC-P, ICC\/IF, FC, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200  IP: 1\/20  FC: 1\/50-1\/100\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Receptor with high affinity for TNFSF2\/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1\/lymphotoxin-alpha. The TRAF1\/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B\/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 48 kDa; Observed MW: 65 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of TNF Receptor II in 3T3, C6 lysates using TNF Receptor 2 antibody., Western blot analysis of TNF Receptor II in Jurkat, Hela lysates using TNF Receptor II antibody., Immunocytochemistry analysis of TNF Receptor II in Hela using TNF Receptor II antibody, and DAPI, Immunohistochemistry analysis of paraffin-embedded Human lung cancer using TNF Receptor II antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CD120b; p75 TNF receptor; p80 TNF alpha receptor; Soluble TNFR1B variant 1; TBP-2; TBPII; TNF R75; TNFBR; TNFR-II; TNFR1B; TNFR2; TNFR80; TNFRII; Tnfrsf1b\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human TNF Receptor II\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43044068786355,"sku":"BZ16979-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43044068819123,"sku":"BZ16979-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_37ccc139-90fe-4dc2-9a4a-d485f2b85e35.jpg?v=1707739476","url":"https:\/\/afsbio.com\/products\/tnf-receptor-2-polyclonal-antibody-bz16979","provider":"AFSBio Inc.","version":"1.0","type":"link"}