{"product_id":"tnf-rii-tnfrsf1b-cd120b-rabbit-pab-a24513","title":"TNF RII\/TNFRSF1B\/CD120b Rabbit pAb - A24513","description":"\u003cp\u003eTNF RII\/TNFRSF1B\/CD120b Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A24513-20, A24513-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables tumor necrosis factor-activated receptor activity. Involved in several processes, including negative regulation of extracellular matrix constituent secretion; regulation of nervous system development; and semi-lunar valve development. Acts upstream of or within several processes, including RNA destabilization; apoptotic signaling pathway; and negative regulation of inflammatory response. Located in membrane raft. Is expressed in several structures, including blood; dorsal aorta; extraembryonic component; genitourinary system; and liver. Human ortholog (s) of this gene implicated in several diseases, including Parkinsonism; acne; bone disease (multiple) ; glomerulonephritis (multiple) ; and lung disease (multiple) . Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B) .\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 50kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 50kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment) .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 21938\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P25119\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2; TNF RII\/TNFRSF1B\/CD120b\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Apoptosis, Receptors, Receptor Processing.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Tnfrsf1b\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189852463283,"sku":"A24513-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189852496051,"sku":"A24513-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_a82e8098-ffde-4622-9658-eb0e1bd5d03a.png?v=1766436790","url":"https:\/\/afsbio.com\/products\/tnf-rii-tnfrsf1b-cd120b-rabbit-pab-a24513","provider":"AFSBio Inc.","version":"1.0","type":"link"}