{"product_id":"tnfalpha-polyclonal-antibody-bt-ap15036","title":"TNFAlpha Polyclonal Antibody - BT-AP15036","description":"\u003cp\u003eTNFAlpha Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15036-20, BT-AP15036-50, BT-AP15036-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A\/TNFR1 and TNFRSF1B\/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Cardiovascular; Cancer; Microbiology; Metabolism; Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TNF\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Tumor necrosis factor\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P01375; Mouse: P06804; Rat: P16599\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Tumor necrosis factor;Cachectin;TNF-alpha;Tumor necrosis factor ligand superfamily member 2;TNF-a [Cleaved into: Tumor necrosis factor, membrane form;N-terminal fragment;NTF; Intracellular; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Tumor necrosis factor, membrane form; N-terminal fragment; NTF; Intracellular domain 1; ICD1; Intracellular domain 2; ICD2; C-domain 1; C-domain 2; Tumor necrosis factor, soluble form;\u003c\/p\u003e \n\n\u003cp\u003eGeneID: Human: 7124\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239391584435,"sku":"BT-AP15036-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239391617203,"sku":"BT-AP15036-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239391649971,"sku":"BT-AP15036-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_aa3d7918-1c49-410d-a16f-bbd26b758db0.png?v=1769393888","url":"https:\/\/afsbio.com\/products\/tnfalpha-polyclonal-antibody-bt-ap15036","provider":"AFSBio Inc.","version":"1.0","type":"link"}