{"product_id":"tnfrsf1a-monoclonal-antibody-bt-mca3946","title":"TNFRSF1A Monoclonal Antibody - BT-MCA3946","description":"\u003cp\u003eTNFRSF1A Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3946-50, BT-MCA3946-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TNFRSF1A\u003c\/p\u003e\n\n\u003cp\u003eApplications: ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2G11C9\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TNFRSF1A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human TNFRSF1A (AA: extra 30-211) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 51KDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P19438\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: FPF, p55, p60, TBP1, TNF-R, TNFAR, TNFR1, p55-R, CD120a, TNFR55, TNFR60, TNF-R-I, TNF-R55\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7132\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238522052787,"sku":"BT-MCA3946-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238522085555,"sku":"BT-MCA3946-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4a1f2875-f9e2-4b5f-8602-cac3cab95c75.png?v=1769382144","url":"https:\/\/afsbio.com\/products\/tnfrsf1a-monoclonal-antibody-bt-mca3946","provider":"AFSBio Inc.","version":"1.0","type":"link"}