{"product_id":"tnfsf9-monoclonal-antibody-bt-mca4048","title":"TNFSF9 Monoclonal Antibody - BT-MCA4048","description":"\u003cp\u003eTNFSF9 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4048-50, BT-MCA4048-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9\/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9\/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9\/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TNFSF9\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2B7B8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TNFSF9\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human TNFSF9 (AA: Extra(50-254)) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 27kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P41273\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CD137L, TNLG5A, 4-1BB-L\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8744\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238389899443,"sku":"BT-MCA4048-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238389932211,"sku":"BT-MCA4048-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b28e83fe-8fcf-44bc-86ed-2957513dcfc4.png?v=1769379779","url":"https:\/\/afsbio.com\/products\/tnfsf9-monoclonal-antibody-bt-mca4048","provider":"AFSBio Inc.","version":"1.0","type":"link"}