{"product_id":"tnnc1-polyclonal-antibody-e-ab-60505","title":"TNNC1 Polyclonal Antibody - E-AB-60505","description":"\u003cp\u003eTNNC1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60505-60, E-AB-60505-120, E-AB-60505-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TNNC1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TNNC1; CMD1Z; CMH13; TN-C; TNC; TNNC; troponin C1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Cardiovascular,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P63316\u003c\/p\u003e\n\n\u003cp\u003eBackground: Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TNNC1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 18kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 16kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146074325171,"sku":"E-AB-60505-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146074390707,"sku":"E-AB-60505-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146074423475,"sku":"E-AB-60505-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_7d8af081-bfdd-409f-a724-91d83fad4184.png?v=1710290739","url":"https:\/\/afsbio.com\/products\/tnnc1-polyclonal-antibody-e-ab-60505","provider":"AFSBio Inc.","version":"1.0","type":"link"}