{"product_id":"tnni3-polyclonal-antibody-e-ab-61454","title":"TNNI3 Polyclonal Antibody - E-AB-61454","description":"\u003cp\u003eTNNI3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61454-60, E-AB-61454-120, E-AB-61454-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TNNI3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TNNI3; CMD1FF; CMD2A; CMH7; RCM1; TNNC1; cTnI; troponin I3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Developmental Biology, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P19429\u003c\/p\u003e\n\n\u003cp\u003eBackground: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TNNI3 (NP_000354.4).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IF \t1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 24kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 26kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146167320755,"sku":"E-AB-61454-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146167353523,"sku":"E-AB-61454-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146167386291,"sku":"E-AB-61454-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9d56b4ea-fa23-45ec-9a2a-78b0fb0793eb.png?v=1710291509","url":"https:\/\/afsbio.com\/products\/tnni3-polyclonal-antibody-e-ab-61454","provider":"AFSBio Inc.","version":"1.0","type":"link"}