{"product_id":"tnr18-polyclonal-antibody-bt-ap15055","title":"TNR18 Polyclonal Antibody - BT-AP15055","description":"\u003cp\u003eTNR18 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15055-20, BT-AP15055-50, BT-AP15055-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Immunology; Cell biology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TNFRSF18\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Tumor necrosis factor receptor superfamily member 18\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9Y5U5; Mouse: O35714\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Tumor necrosis factor receptor superfamily member 18;Activation-inducible TNFR family receptor;Glucocorticoid-induced TNFR-related protein;CD antigen CD357\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8784\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239392698547,"sku":"BT-AP15055-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239392731315,"sku":"BT-AP15055-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239392764083,"sku":"BT-AP15055-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3155f5cc-43c6-4dec-a754-d458841ed95d.png?v=1769393904","url":"https:\/\/afsbio.com\/products\/tnr18-polyclonal-antibody-bt-ap15055","provider":"AFSBio Inc.","version":"1.0","type":"link"}