{"product_id":"top1-monoclonal-antibody-bt-mca4743","title":"TOP1 Monoclonal Antibody - BT-MCA4743","description":"\u003cp\u003eTOP1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4743-50, BT-MCA4743-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TOP1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3D4B1\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TOP1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human TOP1 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 90.7kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P11387\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TOPI\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7150\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238516351155,"sku":"BT-MCA4743-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238516383923,"sku":"BT-MCA4743-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_01298fba-eda1-4c29-a169-0fdf0562a286.png?v=1769381997","url":"https:\/\/afsbio.com\/products\/top1-monoclonal-antibody-bt-mca4743","provider":"AFSBio Inc.","version":"1.0","type":"link"}