{"product_id":"topo-iiiα-rabbit-pab-es8351","title":"Topo IIIα rabbit pAb - ES8351","description":"\u003cp\u003eTopo IIIα rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8351-50, ES8351-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from Topo IIIα . at AA range: 350-430\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 115kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 7156\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q13472\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Mitochondrion matrix.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202374688947,"sku":"ES8351-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202374721715,"sku":"ES8351-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_1e4e2e74-74cb-470c-8659-477dd4b413eb.png?v=1767127786","url":"https:\/\/afsbio.com\/products\/topo-iii%ce%b1-rabbit-pab-es8351","provider":"AFSBio Inc.","version":"1.0","type":"link"}