{"product_id":"toprs-polyclonal-antibody-bt-ap15076","title":"TOPRS Polyclonal Antibody - BT-AP15076","description":"\u003cp\u003eTOPRS Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15076-20, BT-AP15076-50, BT-AP15076-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a nuclear protein which is serine and arginine rich, and contains a RING-type zinc finger domain. It is highly expressed in the testis, and functions as an ubiquitin-protein E3 ligase. Mutations in this gene are associated with retinitis pigmentosa type 31. Alternatively spliced transcript variants, encoding different isoforms, have been observed for this locus.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TOPORS\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: E3 ubiquitin-protein ligase Topors\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9NS56; Mouse: Q80Z37\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: E3 ubiquitin-protein ligase Topors;EC 6.3.2.-;SUMO1-protein E3 ligase Topors;Topoisomerase I-binding RING finger protein;Topoisomerase I-binding arginine\/serine-rich protein;Tumor suppressor\u003c\/p\u003e \n\n\u003cp\u003eGeneID: Human: 10210\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239393484979,"sku":"BT-AP15076-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239393517747,"sku":"BT-AP15076-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239393550515,"sku":"BT-AP15076-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e5e35dd4-80b3-4e9a-9bba-9988ab8a30ad.png?v=1769393915","url":"https:\/\/afsbio.com\/products\/toprs-polyclonal-antibody-bt-ap15076","provider":"AFSBio Inc.","version":"1.0","type":"link"}