{"product_id":"torc1-monoclonal-antibody-mb0169","title":"TORC1 Monoclonal Antibody-MB0169","description":"\u003cp\u003eTORC1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgM, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB0169-50, MB0169-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q6UUV9\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse IgM\u003c\/p\u003e\n\n\u003cp\u003eTORC1 Monoclonal Antibody-MB0169\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Monkey\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB,\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:1000~2000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.Acts as a coactivator, in the SIK\/TORC signaling pathway,being active when dephosphorylated and acts independently of CREB1 ´Ser-133´ phosphorylation.Enhances the interaction of CREB1 with TAF4.Regulates the expression of specific CREB-activated genes such as the steroidogenic gene,StAR.Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses.May be required for dendritic growth of developing cortical neurons.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of TORC1 and does not cross-react with related proteins\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Predicted band size:78KDa\u003cbr\u003e\nObserved band size:78KDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blotDetection of TORC1 mAb in Hela, mouse brain, SW480, COS7, C6 and 3T3 cellLysates using TORC1 mAb (1:2000 diluted) ., Western blot (WB) analysis of TORC1 mAb at 1:5000 dillution\u003cbr\u003e\n Lane 1: HeLa whole cell lysate (30μg) \u003cbr\u003e\n Lane 2: NIH-3T3 whole cell lysate (30μg) \u003cbr\u003e\n Lane 3: The Brain tissue lysate of Rat (30μg) \u003cbr\u003e\n Lane 4: H9C2 whole cell lysate (40μg)\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: KIAA0616; CREB regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CRTC1; CRTC1; FLJ14027; KIAA0616; MECT 1; Mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC-1; TORC1; Transducer of CREB protein 1; Transducer of regulated cAMP response element binding protein 1; Transducer of regulated cAMP response element-binding protein (CREB) 1; Transducer of regulated cAMP response element-binding protein 1; WAMTP1; MECT1; TORC1; TORC-1; WAMTP1.\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human TORC1.\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962828034227,"sku":"MB0169-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962828066995,"sku":"MB0169-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_cd1485d8-833b-4fbd-8a91-6193b30934a6.jpg?v=1705319187","url":"https:\/\/afsbio.com\/products\/torc1-monoclonal-antibody-mb0169","provider":"AFSBio Inc.","version":"1.0","type":"link"}