{"product_id":"torc1-n-terminus-monoclonal-antibody-mb0104","title":"TORC1 (N-terminus) Monoclonal Antibody-MB0104","description":"\u003cp\u003eTORC1 (N-terminus) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB0104-50, MB0104-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgM, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q6UUV9\u003c\/p\u003e \n\n\u003cp\u003eHost: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, FC, ICC, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:1000\u003cbr\u003e\nICC: 1:100~300\u003cbr\u003e\nIP: 1:50~200 \u003cbr\u003e\nFC: 1:50~100\u003c\/p\u003e\n\n\u003cp\u003eBackground: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK\/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 ´Ser-133´ phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses (By similarity)\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of TORC1 and does not cross-react with related proteins\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Predicted band size: 69KDa \u003cbr\u003e\nObserved band size: 69KDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot detection of TORC1 (N-terminus) antibody in Hela and Jurkat lysates using TORC1 (N-terminus) antibody (1:1000 diluted)., Flow Cytometry analysis of K562 cells stained with TORC1(N-terminus) (red, 1\/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG., Immunocytochemistry stain of Hela using TORC1 antibody (1:300)., Immunoprecipitation analysis of Hela cell lysate using CRTC1 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: KIAA0616; CREB regulated transcription coactivator 1; CREB-regulated transcription coactivator 1; CRTC1; CRTC1; FLJ14027; KIAA0616; MECT 1; Mucoepidermoid carcinoma translocated 1; Mucoepidermoid carcinoma translocated protein 1; TORC-1; TORC1; Transducer of CREB protein 1; Transducer of regulated cAMP response element binding protein 1; Transducer of regulated cAMP response element-binding protein (CREB) 1; Transducer of regulated cAMP response element-binding protein 1; WAMTP1; MECT1; TORC1; WAMTP1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to the N-terminus of Human TORC1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43050226581683,"sku":"MB0104-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43050226614451,"sku":"MB0104-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5dfd7987-b5cd-4f93-aa4d-806070bfd3d3.jpg?v=1707913635","url":"https:\/\/afsbio.com\/products\/torc1-n-terminus-monoclonal-antibody-mb0104","provider":"AFSBio Inc.","version":"1.0","type":"link"}