{"product_id":"tp4a2-polyclonal-antibody-bt-ap15079","title":"TP4A2 Polyclonal Antibody - BT-AP15079","description":"\u003cp\u003eTP4A2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP15079-20, BT-AP15079-50, BT-AP15079-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cell biology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PTP4A2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Protein tyrosine phosphatase type IVA 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q12974; Mouse: O70274; Rat: Q6P9X4\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Protein tyrosine phosphatase type IVA 2;EC 3.1.3.48;HU-PP-1;OV-1;PTP;CAAXII;Protein-tyrosine phosphatase 4a2;Protein-tyrosine phosphatase of regenerating liver 2;PRL-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8073\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239393779891,"sku":"BT-AP15079-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239393812659,"sku":"BT-AP15079-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239393845427,"sku":"BT-AP15079-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f7d3f103-2db5-488c-9217-d5b5e22b94a0.png?v=1769393918","url":"https:\/\/afsbio.com\/products\/tp4a2-polyclonal-antibody-bt-ap15079","provider":"AFSBio Inc.","version":"1.0","type":"link"}