{"product_id":"tph1-phospho-ser58-rabbit-pab-es7442","title":"TPH1 (phospho Ser58) rabbit pAb - ES7442","description":"\u003cp\u003eTPH1 (phospho Ser58) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES7442-50, ES7442-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: TPH1; TPH; TPRH; TRPH; Tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human Tryptophan Hydroxylase around the phosphorylation site of Ser58. AA range:26-75\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 51kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 7166\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P17752\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: cytosol, neuron projection,\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202342772915,"sku":"ES7442-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202342805683,"sku":"ES7442-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_774b7634-cea6-4d66-b7af-0e0165f0af7c.png?v=1767127037","url":"https:\/\/afsbio.com\/products\/tph1-phospho-ser58-rabbit-pab-es7442","provider":"AFSBio Inc.","version":"1.0","type":"link"}