{"product_id":"tph1-polyclonal-antibody-bt-ap09151","title":"TPH1 Polyclonal Antibody - BT-AP09151","description":"\u003cp\u003eTPH1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09151-20, BT-AP09151-50, BT-AP09151-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: TPH1 encodes a member of the aromatic amino acid hydroxylase family. The tryptophan 5-hydroxylase 1 catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TPH1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TPH1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 50985\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P17752; Mouse: P17532; Rat: P09810\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TPH1; TPH; TPRH; TRPH; Tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 7166; Mouse: 21990; Rat: 24848\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239956603059,"sku":"BT-AP09151-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239956635827,"sku":"BT-AP09151-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239956668595,"sku":"BT-AP09151-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0d971a51-be8a-4a57-85cf-1e60633f0cd0.png?v=1769401415","url":"https:\/\/afsbio.com\/products\/tph1-polyclonal-antibody-bt-ap09151","provider":"AFSBio Inc.","version":"1.0","type":"link"}