{"product_id":"tpo-polyclonal-antibody-e-ab-14412","title":"TPO Polyclonal Antibody - E-AB-14412","description":"\u003cp\u003eTPO Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-14412-60, E-AB-14412-120, E-AB-14412-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TPO\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: MSA; PERT; TDH2A; Thyroid microsomal antigen; Thyroid peroxidase; Thyroperoxidase; TPO; TPX\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Neuroscience, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P07202\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human TPO\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:25-1:100\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124151713971,"sku":"E-AB-14412-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124151746739,"sku":"E-AB-14412-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124151779507,"sku":"E-AB-14412-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c06588f3-d104-4712-87c0-d92932ca206c.png?v=1709724819","url":"https:\/\/afsbio.com\/products\/tpo-polyclonal-antibody-e-ab-14412","provider":"AFSBio Inc.","version":"1.0","type":"link"}