{"product_id":"tpx2-rabbit-pab-es5280","title":"TPX2 rabbit pAb - ES5280","description":"\u003cp\u003eTPX2 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES5280-50, ES5280-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: developmental stage:Exclusively expressed in proliferating cells from the transition G1\/S until the end of cytokinesis., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., subcellular location:During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus., tissue specificity:Expressed in lung carcinoma cell lines but not in normal lung tissues.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: TPX2; C20orf1; C20orf2; DIL2; HCA519; Targeting protein for Xklp2; Differentially expressed in cancerous and non-cancerous lung cells 2; DIL-2; Hepatocellular carcinoma-associated antigen 519; Protein fls353; Restricted expression prolifera\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human DIL-2. AA range:301-350\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 86kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 22974\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9ULW0\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202239422643,"sku":"ES5280-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202239455411,"sku":"ES5280-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_31e8c4ec-c079-4908-b735-16d007e17804.png?v=1767124866","url":"https:\/\/afsbio.com\/products\/tpx2-rabbit-pab-es5280","provider":"AFSBio Inc.","version":"1.0","type":"link"}