{"product_id":"tradd-polyclonal-antibody-e-ab-92102","title":"TRADD Polyclonal Antibody - E-AB-92102","description":"\u003cp\u003eTRADD Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92102-60, E-AB-92102-120, E-AB-92102-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TRADD\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TRADD; Hs.89862; TNFRSF1A associated via death domain\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q15628\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A\/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6\/FAS and adaptor protein FADD\/MORT1, and is involved in the Fas-induced cell death pathway.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TRADD\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 27kDa\/34kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 32KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146625646771,"sku":"E-AB-92102-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146625679539,"sku":"E-AB-92102-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146625712307,"sku":"E-AB-92102-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4ce345ca-a675-4294-9667-445415a6e2a7.png?v=1710298734","url":"https:\/\/afsbio.com\/products\/tradd-polyclonal-antibody-e-ab-92102","provider":"AFSBio Inc.","version":"1.0","type":"link"}