{"product_id":"traf3-polyclonal-antibody-e-ab-66426","title":"TRAF3 Polyclonal Antibody - E-AB-66426","description":"\u003cp\u003eTRAF3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-66426-60, E-AB-66426-120, E-AB-66426-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TRAF3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TRAF3; CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Immunology,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q13114\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human TRAF3\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 55kDa\/64kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 64kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146415734963,"sku":"E-AB-66426-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146415767731,"sku":"E-AB-66426-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146415800499,"sku":"E-AB-66426-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5ee386c0-f86b-43bb-8154-15d2846a73fa.png?v=1710295191","url":"https:\/\/afsbio.com\/products\/traf3-polyclonal-antibody-e-ab-66426","provider":"AFSBio Inc.","version":"1.0","type":"link"}