{"product_id":"traf4-polyclonal-antibody-bt-ap09170","title":"TRAF4 Polyclonal Antibody - BT-AP09170","description":"\u003cp\u003eTRAF4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP09170-20, BT-AP09170-50, BT-AP09170-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: TRAF4 (TNF receptor associated factor 4) encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR\/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8\/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TRAF4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TRAF4 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 53543\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9BUZ4; Mouse: Q61382\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: TRAF4; CART1; MLN62; RNF83; TNF receptor-associated factor 4; Cysteine-rich domain associated with RING and Traf domains protein 1; Metastatic lymph node gene 62 protein; MLN 62; RING finger protein 8\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 9618; Mouse: 22032\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239957717171,"sku":"BT-AP09170-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239957749939,"sku":"BT-AP09170-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239957782707,"sku":"BT-AP09170-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8460a9d9-0bd8-4e94-a811-d7e784ad6d91.png?v=1769401433","url":"https:\/\/afsbio.com\/products\/traf4-polyclonal-antibody-bt-ap09170","provider":"AFSBio Inc.","version":"1.0","type":"link"}