{"product_id":"traf4-polyclonal-antibody-e-ab-61491","title":"TRAF4 Polyclonal Antibody - E-AB-61491","description":"\u003cp\u003eTRAF4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61491-60, E-AB-61491-120, E-AB-61491-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TRAF4\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TRAF4; CART1; MLN62; RNF83\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9BUZ4\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR\/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8\/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TRAF4 (NP_004286.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF 1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136848822451,"sku":"E-AB-61491-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136848855219,"sku":"E-AB-61491-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136848887987,"sku":"E-AB-61491-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_dd5975fe-3017-4e45-9110-5a5f927584e7.png?v=1709992659","url":"https:\/\/afsbio.com\/products\/traf4-polyclonal-antibody-e-ab-61491","provider":"AFSBio Inc.","version":"1.0","type":"link"}