{"product_id":"transcription-factor-7-like-2-polyclonal-antibody-bz16685","title":"Transcription Factor 7 Like 2 Polyclonal Antibody-BZ16685","description":"\u003cp\u003eTranscription Factor 7 Like 2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16685-50, BZ16685-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9NQB0\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eTranscription Factor 7 Like 2 Polyclonal Antibody-BZ16685\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, ICC\/IF, IP, , FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000 IHC: 1\/50-1\/100 IF: 1\/50-1\/200 IP: 1\/20 FC: 1\/50-1\/100\u003c\/p\u003e\n\n\u003cp\u003eBackground: Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2\/TCF4 and CTNNB1.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 68 kDa; Observed MW: 68 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of TCF7L2 in JurkatLysates using Transcription Factor 7 Like 2 antibody., Immunohistochemistry analysis of paraffin-embedded Human colonic cancer using TCF7L2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: TCF7L2; HMG box transcription factor 4; HTCF-4; T-cell factor-4 variant X2; T-cell factor 4; Transcription factor 7-like 2; TCF-4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human TCF7L2\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42957328023731,"sku":"BZ16685-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42957328056499,"sku":"BZ16685-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_9fae401e-8271-4369-a135-e9f9306af03e.jpg?v=1705144907","url":"https:\/\/afsbio.com\/products\/transcription-factor-7-like-2-polyclonal-antibody-bz16685","provider":"AFSBio Inc.","version":"1.0","type":"link"}